Escherichia coli in the human intestine
Samuel Ellis, QIB
Enteroaggregative E. coli adheres to cells in the human intestine in a ‘stacked brick’ pattern and is often associated with diarrhoeal illness. Scientists at the Institute of Food Research (now QIB) and the University of East Anglia on the Norwich Research Park are undertaking innovative research to generate new knowledge of the mechanisms underpinning gut health.
In this study E. coli strain 042 was incubated with polarised T84 human intestinal epithelial cells under microaerobic conditions for 4 hours. Cells were then fixed and immunofluorescent labelling was performed to show nuclei (blue), actin (green) and E. coli (red). 20x magnification image.